شحة النوم تؤدي إلى زيادة تنشيط مناطق الدماغ الحساسة لمحفزات الطعام



شحة النوم تؤدي إلى زيادة تنشيط مناطق الدماغ الحساسة لمحفزات الطعام


Sleep restriction leads to increased activation of brain regions sensitive to food stimuli.

Abstract

Background: Epidemiologic evidence shows an increase in obesity concurrent with a reduction in average sleep duration among Americans. Although clinical studies propose that restricted sleep affects hormones related to appetite, neuronal activity in response to food stimuli after restricted and habitual sleep has not been investigated.

تظهر الأدلة الوبائية زيادة في السمنة المتزامنة مع انخفاض في متوسط ​​مدة النوم بين قسم من البشر. على الرغم من أن الدراسات السريرية تشير إلى أن النوم الشحيح يؤثر على الهرمونات المتعلقة بالشهية إلا أنَّ نشاط الخلايا العصبية استجابة لمحفزات الطعام بعد النوم الشحيح والمعتاد لم يتم التحقيق فيه. وفي هذا الصدد بيَّنت احدى الدراسات أنَّ ثمة رابطة بين شحة النوم والإستعداد لحوافز الطعام وأنَّها تنسجم مع الملاحظة أنَّ شحة النوم قد تؤدي الى ميل أكبر الى تناول الطعام.

Marie-Pierre St-Onge, et al. Sleep restriction leads to increased activation of brain regions sensitive to food stimuli. Am J Clin Nutr; 2012 Apr;95(4):818-24.



Objective: The objective of this study was to determine the effects of partial sleep restriction on neuronal activation in response to food stimuli.

Design: Thirty healthy, normal-weight [BMI (in kg/m²): 22-26] men and women were recruited (26 completed) to participate in a 2-phase inpatient crossover study in which they spent either 4 h/night (restricted sleep) or 9 h/night (habitual sleep) in bed. Each phase lasted 6 d, and functional magnetic resonance imaging was performed in the fasted state on day 6.

Results: Overall neuronal activity in response to food stimuli was greater after restricted sleep than after habitual sleep. In addition, a relative increase in brain activity in areas associated with reward, including the putamen, nucleus accumbens, thalamus, insula, and prefrontal cortex in response to food stimuli, was observed.

Conclusion: The findings of this study link restricted sleep and susceptibility to food stimuli and are consistent with the notion that reduced sleep may lead to greater propensity to overeat.


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